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Histone methylation modifiers in medical therapeutics - ScienceDirect
Histone methylation modifiers in medical therapeutics - ScienceDirect

Luke B. Hesson · Antonia L. Pritchard Editors
Luke B. Hesson · Antonia L. Pritchard Editors

An Alternative Approach to ChIP-Seq Normalization Enables Detection of  Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2  Inhibition | PLOS ONE
An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition | PLOS ONE

Full article: Epigenetic modification in chromatin machinery and its  deregulation in pediatric brain tumors: Insight into epigenetic therapies
Full article: Epigenetic modification in chromatin machinery and its deregulation in pediatric brain tumors: Insight into epigenetic therapies

High-throughput screening with nucleosome substrate identifies  small-molecule inhibitors of the human histone lysine methyltransferase  NSD2 - ScienceDirect
High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2 - ScienceDirect

KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic  Vulnerability in Lung Cancer - ScienceDirect
KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer - ScienceDirect

Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling  in KMT2D Mutant Melanoma - ScienceDirect
Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma - ScienceDirect

Histone methylation modifiers in medical therapeutics - ScienceDirect
Histone methylation modifiers in medical therapeutics - ScienceDirect

IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in  Chromatin Remodeling and Disease Development
IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development

Histone methylation modifiers in medical therapeutics - ScienceDirect
Histone methylation modifiers in medical therapeutics - ScienceDirect

Transcriptional Regulation and Its Misregulation in Disease: Cell
Transcriptional Regulation and Its Misregulation in Disease: Cell

Transcriptional Regulation and Its Misregulation in Disease: Cell
Transcriptional Regulation and Its Misregulation in Disease: Cell

Design, synthesis and biological evaluation of novel  1-methyl-3-oxo-2,3,5,6,7,8-hexahydroisoquinolins as potential EZH2  inhibitors - RSC Advances (RSC Publishing) DOI:10.1039/C5RA02365C
Design, synthesis and biological evaluation of novel 1-methyl-3-oxo-2,3,5,6,7,8-hexahydroisoquinolins as potential EZH2 inhibitors - RSC Advances (RSC Publishing) DOI:10.1039/C5RA02365C

IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in  Chromatin Remodeling and Disease Development
IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development

IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in  Chromatin Remodeling and Disease Development
IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development

High-throughput screening with nucleosome substrate identifies  small-molecule inhibitors of the human histone lysine methyltransferase  NSD2 - Journal of Biological Chemistry
High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2 - Journal of Biological Chemistry

Synthesis and biological evaluation of benzomorpholine derivatives as novel  EZH2 inhibitors for anti-non-small cell lung cancer activity | SpringerLink
Synthesis and biological evaluation of benzomorpholine derivatives as novel EZH2 inhibitors for anti-non-small cell lung cancer activity | SpringerLink

High-throughput screening with nucleosome substrate identifies  small-molecule inhibitors of the human histone lysine methyltransferase  NSD2 - ScienceDirect
High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2 - ScienceDirect

IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in  Chromatin Remodeling and Disease Development
IJMS | Free Full-Text | Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development

KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic  Vulnerability in Lung Cancer
KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer

Synthesis and biological evaluation of benzomorpholine derivatives as novel  EZH2 inhibitors for anti-non-small cell lung cancer activity | SpringerLink
Synthesis and biological evaluation of benzomorpholine derivatives as novel EZH2 inhibitors for anti-non-small cell lung cancer activity | SpringerLink

PDF) Targeting Histone Lysine Methylation in Cancer
PDF) Targeting Histone Lysine Methylation in Cancer

berry (@berry46566269) / Twitter
berry (@berry46566269) / Twitter

Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling  in KMT2D Mutant Melanoma. - Abstract - Europe PMC
Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma. - Abstract - Europe PMC

Targeting histone lysine methylation in cancer - ScienceDirect
Targeting histone lysine methylation in cancer - ScienceDirect

IJMS | Free Full-Text | Epigenetic Control of a Local Chromatin Landscape
IJMS | Free Full-Text | Epigenetic Control of a Local Chromatin Landscape